Dott.ssa Simona Censi

Specialista in Endocrinologia

1/10/2021- attualmente
Master in Biostatistica per la ricerca e la pubblicazione scientifica, master di I livello, Università degli Studi di Padova

1/10/2018 – 10/02/2022
Dottorato in “Medicina specialistica traslazionale G.B. Morgagni”, XXXIV ciclo, conseguita presso l’Università degli Studi di Padova, Voto finale: eccellente con lode

01/01/2020- 14/01/2022
Assegnataria di borsa di ricerca intitolata “Validazione del ruolo diagnostico e terapeutico dei miRNA come biomarkers prognostici e diagnostici e possibili target terapeutici del carcinoma midollare della tiroide nei pazienti con syndrome MEN2” presso il Dipartimento di Medicina (DIMED) dell’Università degli Studi di Padova.

01/07/2019-01/09/2019
Assegnataria di borsa di ricerca intitolata “ Ruolo del calcifediolo e del colecalciferolo nei meccanismi di regolazione intracellulare degli adenoma paratiroidei: correlazione con l’espressione del CaSR” presso il Dipartimento di Medicina (DIMED) dell’ Università degli Studi di Padova.

01/01/2019-01/03/2019
Assegnataria di borsa di ricerca intitolata “Ruolo del calcifediolo e del colecalciferolo nelle cellule tiroidee: possibili effetti sul tessuto normale e nella tiroidite cronica autoimmune”, presso il Dipartimento di Medicina (DIMED) dell’ Università degli Studi di Padova.

 

08/08/2013–03/09//2018
Specializzazione in Endocrinologia e Malattie del Metabolismo, conseguita presso l’Università degli Studi di Padova, Voto finale: 110/110 e lode

Attività svolta presso l’Unità Operativa di Endocrinologia, Azienda Ospedaliera/Università di Padova, Padova (Italia), durante la specializzazione:

• Assistenza clinica
• Ricerca clinica

Campi di interesse: Endocrinologia clinica, patologia tiroidea, ipofisaria, surrenalica, paratiroidea, del metabolismo osseo, tumori neuroendocrini, endocrinologia ginecologica, diabete, auxologia, endocrinologia pediatrica e adolescentologia
Titolo della tesi di specializzazione “Caratteristiche molecolari e cliniche di una serie monocentrica di
carcinomi tiroidei in età pediatrica”

2006–2012
“Laurea in Medicina e Chirurgia,
conseguita presso la Facoltà di Medicina e Chirurgia dell’Università degli Studi di Padova
Voto di laurea: 110/110 e lode”

Giannone M, Dalla Costa M, Sabbadin C, Garelli S, Salvà M, Masiero S, Plebani M, Faggian D, Gallo N, Presotto F, Bertazza L, Nacamulli D, Censi S, Mian C, Betterle C. TSH-receptor autoantibodies in patients with chronic thyroiditis and hypothyroidism. Clin Chem Lab Med. 2022 May 5;60(7):1020-1030

Manso J, Bertazza L, Barollo S, Mondin A, Censi S, Carducci S, Ferrara AM, Boschin IM, Zovato S, Schiavi F, Gregianin M, Pennelli G, Iacobone M, Mian C. Overexpression of miR-375 and L-type Amino Acid Transporter 1 in Pheochromocytoma and Their Molecular and Functional Implications. Int J Mol Sci. 2022 Feb 22;23(5):2413

Galuppini F, Censi S, Merante Boschin I, Fassan M, Sbaraglia M, Valeri N, Hahne JC, Bertazza L, Munari G, Galasso M, Cascione L, Barollo S, Rugge M, Vianello F, Dei Tos AP, Mian C, Pennelli G. Papillary Thyroid Carcinoma: Molecular Distinction by MicroRNA Profiling. Front Endocrinol (Lausanne). 2022 2022 Feb 23;13:834075

Censi S, De Rosa A, Galuppini F, Manso J, Bertazza L, Merante-Boschin I, Plebani M, Faggian D, Pennelli G, Barollo S, Vianello F, Iacobone M, Mian C. Can ultrasensitive thyroglobulin immunoassays avoid the need for ultrasound in thyroid cancer follow-up? Endocrine. 2021 Nov 20 Mar;75(3):837-845.

Manso J, Zhu YH, Margoni M, Rinaldi F, Censi S, Carducci S, Cosma C, Plebani M, Gallo P, Mian C. Alemtuzumab-induced autoimmune thyroid events in patients with relapsing-remitting multiple sclerosis: A real-life and monocentric experience at a tertiary-level centre. Clin Endocrinol (Oxf). 2021 Nov 1.Online ahead of print

Censi S, Di Stefano M, Repaci A, Benvenuti T, Manso J, Pagotto U, Iacobone M, Barollo S, Bertazza L, Galuppini F, Benna C, Pennelli G, Plebani M, Faggian D, Colombo C, Fugazzola L, Mian C. Basal and Calcium-Stimulated Procalcitonin for the Diagnosis of Medullary Thyroid Cancers: Lights and Shadows. Front Endocrinol (Lausanne). 2021 Oct 13;12:754565.

Baldini E, Tuccilli C, Pironi D, Catania A, Tartaglia F, Di Matteo FM, Palumbo P, Arcieri S, Mascagni D, Palazzini G, Tripodi D, Maturo A, Vergine M, Tarroni D, Lori E, Ferent IC, De Vito C, Fallahi P, Antonelli A, Censi S, D’Armiento M, Barollo S, Mian C, Morrone A, D’Andrea V, Sorrenti S, Ulisse S. Expression and Clinical Utility of Transcription Factors Involved in Epithelial-Mesenchymal Transition during Thyroid Cancer Progression. J Clin Med. 2021 Sep 9;10(18):4076.

Galuppini F, Censi S, Moro M, Carraro S, Sbaraglia M, Iacobone M, Fassan M, Mian C, Pennelli G. MicroRNAs in Medullary Thyroid Carcinoma: A State of the Art Review of the Regulatory Mechanisms and Future Perspectives. Cells. 2021 Apr 20;10(4):955;

Vianello F, Censi S, Watutantrige-Fernando S, Barollo S, Zhu YH, Albiger N, Bertazza L, Manso J, Carducci S, Benna C, Iacobone M, Galuppini F, Pennelli G, Mian C. The role of the size in thyroid cancer risk stratification. Sci Rep. 2021 Mar 31;11(1):7303

Censi S, Bertazza L, Piva I, Manso J, Benna C, Iacobone M, Mondin A, Plebani M, Faggian D, Galuppini F, Pennelli G, Barollo S, Mian C. Serum miR-375 for Diagnostic and Prognostic Purposes in Medullary Thyroid Carcinoma. Front Endocrinol (Lausanne). 2021 Mar 29;12:647369.

Manso J, Censi S, Roberti A, Iacobone M, Barollo S, Bertazza L, Galuppini F, Vianello F, Albinger N, Scaroni C, Pennelli G, Mian C. Prognostic significance of the sum of the diameters of single foci in multifocal papillary thyroid cancer: the concept of new-old tumor burden. Ther Adv Endocrinol Metab. 2020 Oct 12;11

Manso J, Censi S, Mian C. Epigenetic in medullary thyroid cancer: the role of microRNA in tumorigenesis and prognosis. Curr Opin Oncol. 2021 Jan;33(1):9-15.

Censi S, Manso J, Barollo S, Mondin A, Bertazza L, De Marchi M, Mian C, On Behalf Of The Food And Nutrition Hygiene Services Sian. Changing Dietary Habits in Veneto Region over Two Decades: Still a Long Road to Go to Reach an Iodine- Sufficient Status. Nutrients. 2020 Aug 11;12(8): E2399.

Fugazzola L, Di Stefano M, Censi S, Repaci A, Colombo C, Grimaldi F, Magri F, Pagotto U, Iacobone M, Persani L, Mian C. Basal and stimulated calcitonin for the diagnosis of medullary thyroid cancer: updated thresholds and safety assessment. J Endocrinol Invest. 2020 Jul 12. doi: 10.1007/s40618-020- 01356-9.

Cavedon E, Manso J, Negro I, Censi S, Serra R, Busetto L, Vettor R, Plebani M, Pezzani R, Nacamulli D, Mian C. Selenium Supplementation, Body Mass Composition, and Leptin Levels in Patients with Obesity on a Balanced Mildly Hypocaloric Diet: A Pilot Study. Int J Endocrinol. 2020 May 28;2020

Manso J, Censi S, Iacobone M, Galuppini F, Pennelli G, Betterle C, Mian C. First proof of association between autoimmune polyglandular syndrome and multiple endocrine neoplasia in humans. Endocr J. 2020 Sep 28;67(9):929-934.

Larsen LV, Mirebeau-Prunier D, Imai T, Alvarez-Escola C, Hasse-Lazar K, Censi S, Castroneves LA, Sakurai A, Kihara M, Horiuchi K, Barbu VD, Borson-Chazot F, Gimenez-Roqueplo AP, Pigny P, Pinson S, Wohllk N, Eng C, Aydogan BI, Saranath D, Dvorakova S, Castinetti F, Patocs A, Bergant D, Links TP, Peczkowska M, Hoff AO, Mian C, Dwight T, Jarzab B, Neumann HPH, Robledo M, Uchino S, Barlier A, Godballe C, Mathiesen JS. Primary hyperparathyroidism as first manifestation in multiple endocrine neoplasia type 2A: an international multicenter study. Endocr Connect. 2020 Jun;9(6):489-497.

Prete A, Borges de Souza P, Censi S, Muzza M, Nucci N, Sponziello M. Update on Fundamental Mechanisms of Thyroid Cancer. Frontiers in Endocrinology 2020 Mar 13;11:10

Censi S, Iacobone M, Simmini S, Manso J, Franceschet G, Plebani M, Frigo AC, Zaninotto M, Torresan F, De Silvestro G, Scaroni C, Mian C, Camozzi V. PTH: Redefining Referenc Ranges in a Healthy Population-The Role of Interfering Factors and the Type of Laboratory Assay. Int J Endocrinol. 2020 Feb21; 2020:1053719.

Censi S, Watutantrige-Fernando S, Groccia G, Manso J, Plebani M, Faggian D, Mion MM, Venturini R, Andrisani A, Casaro A, Vita P, Avogadro A, Camilot M, Scaroni C, Bertazza L, Barollo S, Mian C. The Effects of Iodine Supplementation in Pregnancy on Iodine Status, Thyroglobulin Levels and Thyroid Function Parameters: Results from a Randomized Controlled Clinical Trial in a Mild-to-Moderate Iodine Deficiency Area. Nutrients. 2019 Nov 4;11(11):2639

Galuppini F, Vianello F, Censi S, Barollo S, Bertazza L, Carducci S, Colato C, Manso J, Rugge M, Iacobone M, Watutantrige Fernando S, Pennelli G, Mian C Differentiated Thyroid Carcinoma in Pediatric Age: Genetic and Clinical Scenario. Front Endocrinol (Lausanne). 2019 Aug 7; 10:552.

Censi S, Barollo S, Grespan E, Watutantrige-Fernando S, Manso J, Iacobone M, Casal Ide E, Galuppini F, Fassina A, Bertazza L, Vianello F, Pennelli G, Mian C. Prognostic significance of TERT promoter and BRAF mutations in TIR-4 and TIR-5 thyroid cytology. Eur J Endocrinol. 2019 Jul 1;181(1):1-11.

Pezzani R, Bertazza L, Cavedon E, Censi S, Manso J, Watutantrige-Fernando S, Pennelli G, Galuppini F, Barollo S, Mian C. Novel Prognostic Factors Associated with Cell Cycle Control in Sporadic Medullary Thyroid Cancer Patients. Int J Endocrinol. 2019 Feb 18; 2019:9421079.

Naletto L, Frigo A, Ceccato F, Sabbadin C, Scarpa R, Presotto F, Dalla Costa M, Faggian D, Plebani M, Censi S, Manso J, Furmaniak J, Chen S, Rees Smith B, Masiero S, Pigliaru F, Boscaro M, Scaroni C, Betterle C. The natural history of autoimmune Addison’s disease from the detecion of autoantibodies to development of the disease: a long follow-up study on 143 patients. Eur J Endocrinol. 2019 Mar;180(3):223-234

Franceschet G, Censi S, Cirrone S., Gomiero W, Scaroni C, Camozzi V. Atypical femoral fractures caused by glucocorticoid and bisphosphonate prolonged therapy in premenopausal women: a case report and literature review. Clinical Cases in Mineral and Bone Metabolism 2018; 15(2):227-230

Censi S, Cavedon E, Watutantrige-Fernando S, Barollo S, Bertazza L, Manso J, Maurizio Iacobone, Davide Nacamulli, Francesca Galuppini, Gianmaria Pennelli, Caterina Mian. Unique case of a large indolent medullary thyroid carcinoma: time to reconsider the medullary thyroid adenoma entity? Eur Thyroid J, 2019 Apr;8(2):108-112

Censi S, Manso J, Pandolfo G, Franceschet G, Cavedon E, Zhu YH, Carducci S, Gomiero W, Plebani M, Zaninotto M, Watutantrige-Fernando S, Mian C, Camozzi V. Bone turnover markers, BMD and TBS after short-term, high-dose glucocorticoid therapy in patients with Graves’ orbitopathy: a small prospective pilot study. J Endocrinol Invest. 2019 Jul;42(7):859-865

Censi S, Barollo S, Watutantrige-Fernando S, Manso J, Ferrara AM, Mian C. A novel thyroid hormone receptor beta mutation (G357R) in a family with resistance to thyroid hormone beta: extending the borders of the “Hot” region in the THRB gene. Thyroid Dec 2019 Mar;29(3):449-451

Censi S, Mian C, Betterle C.Insulin autoimmune syndrome: from diagnosis to clinical management. Ann Transl Med. 2018 Sep;6(17):335.

Censi S, Bodanza V, Manso J, Gusella S, Watutantrige-Fernando S, Cavedon E, Barollo S, Bertazza L, Cecchin D, Mian C. Amiodarone-induced thyrotoxicosis: differential diagnosis using 99mTc-sestaMIBI and target-to-background ratio (TBR). Clinical Nuclear Medicine. 2018 Sep;43(9):655-662

Bertazza L, Sensi F, Cavedon E, Watutantrige-Fernando S, Censi S, Manso J, Vianello F, Casal Ide E, Iacobone M, Pezzani R, Mian C, Barollo S. EF24 (a Curcumin Analog) and ZSTK474 Emphasize the Effect of Cabozantinib in Medullary Thyroid Cancer. Endocrinology. 2018 Jun 1;159(6):2348-2360.

Watutantrige-Fernando S, Barollo S, Bertazza L, Cavedon E, Censi S, Manso J, Vianello F; Food Hygiene, Nutrition Services SIAN, Mian C Efficacy of educational intervention to improve awareness of the importance of iodine, use of iodized salt, and dietary iodine intake in northeastern Italian schoolchildren. Nutrition. 2018 Mar 23;53:134-139.

Watutantrige-Fernando S, Vianello F, Barollo S, Bertazza L, Galuppini F, Cavedon E, Censi S, Benna C, Casal Ide E, Parisi A, Nacamulli D, Iacobone M, Pennelli G, Mian C. The Hobnail variant of Papillary Thyroid Carcinoma: clinical/molecular characteristics of a large monocentric series and comparison with conventional histotypes. Thyroid. 2018 Jan;28:96-103.

Censi S, Cavedon E, Bertazza L, Galuppini F, Watutantrige-Fernando S, De Lazzari P, Nacamulli D, Pennelli G, Fassina A, Iacobone M, Casal Ide E, Vianello F, Barollo S, Mian C. Frequency and Significance of Ras, Tert Promoter, and Braf Mutations in Cytologically Indeterminate Thyroid Nodules: A Monocentric Case Series at a Tertiary-Level Endocrinology Unit. Front Endocrinol (Lausanne). 2017 Oct 16;8:273.

Censi S, Albergoni MP, Gallo N, Plebani M, Boscaro M, Betterle C. Insulin autoimmune syndrome (Hirata’s disease) in an Italian patient: a case report and review of the literature. Clinical Chemistry and Laboratory Medicine. 2018 May 24;56(6):889-895

Cavedon E, Barollo S, Bertazza L, Pennelli G, Galuppini F, Watutantrige-Fernando S, Censi S, Iacobone M, Benna C, Vianello F, Zovato S, Nacamulli D and Mian C. Prognostic Impact of miR-224 and RAS Mutations in Medullary Thyroid Carcinoma. International Journal of Endocrinology. 2017. 2017:4915736.

Franceschet G, Mazzucato M, Censi S, Simmini S, Boscaro M, Camozzi V. Is this a seizure? Clinical Cases in Mineral and Bone Metabolism 2017 Jan-Apr;14(1):89-91.

Watutantrige-Fernando S, Barollo S, Bertazza L, Sensi F, Cavedon E, Censi S, Veronese N, Ceccato F, Vianello F, Boscaro M, Nacamulli D, Camozzi V, Mian C. Iodine Status in the Elderly: Association with Milk Intake and Other Dietary Habits. Journal of Nutritional Health & Food Science 2017:5:1-5.

Barollo S, Bertazza L, Watutantrige-Fernando S, Censi S, Cavedon E, Galuppini F, Pennelli G, Fassina A, Citton M, Rubin B, Pezzani R, Benna C, Opocher G, Iacobone M, Mian C. Overexpression of L-Type Amino Acid Transporter 1 (LAT1) and 2 (LAT2): Novel Markers of Neuroendocrine Tumors. Plos One 2016 May 25;11(5):e0156044

Censi S, Cavedon E, Watutantrige-Fernando S, Barollo S, Bertazza L, Zambonin L, Zaninotto M, Faggian D, Plebani M, Mian C. Calcitonin measurement and immunoassay interference: a case report and literature review. Clinical Chemistry and Laboratory Medicine. 2016 Dec 1;54:1861-1870.

Galuppini F, Pennelli G, Vianello F, Censi S, Zambonin L, Watutantrige-Fernando S, Manso J, Nacamulli D, Lora O, Pelizzo MR, Rugge M, Barollo S, Mian C. BRAF analysis before surgery for papillary thyroid carcinoma: correlation with clinicopathological features and prognosis in a single- institution prospective experience. Clinical Chemistry and Laboratory Medicine 2016 Sep 1;54:1531-9.

Censi S, Manso J, Paganini F, Vianello F, Galuppini F, Pennelli G, Iacobone M, Bertazza L, Barollo S, Mian C. Outcome e caratteristiche molecolari della variante hobnail di carcinoma papillare tiroideo. 2- 04/12/2021, 14° Congresso nazionale dell’Associazione Italiana Tiroide (AIT), Pisa, Italia.

Censi S, Watutantrige-Fernando S, Groccia G, Manso J, Plebani M Faggian D, Mion MM, Venturini R, Andrisani A, Casaro A, Vita P, Avogadro A, Camilot M, Scaroni C, Bertazza L, Barollo S – Mian C. “Effetto della supplementazione iodica in gravidanza: risultati di uno studio randomizzato, placebo controllato, condotto in un’area a carenza iodica lieve-moderata”, 05-07/12/2019, 13° Congresso nazionale dell’Associazione Italiana Tiroide (AIT), Genova, Italia.

Censi S, Susi Barollo, Elisabetta Grespan, Sara Watutantrige-Fernando, Elisabetta Cavedon, Jacopo Manso, Maurizio Iacobone, Eric Casal Ide, Francesca Galuppini, Ambrogio Fassina, Gianmaria Pennelli, Federica Vianello, Loris Bertazza, Caterina Mian. “Prognostic significance of TERT promoter and BRAF mutations in cytologically suspicious or malignant thyroid nodules: a monocentric case series at a tertiary-level endocrinology unit” 7-10/10/2019, 42th European Thyroid Association (ATA), Budapest, Hungary

S. Censi, S. Barollo, E. Grespan, S. Watutantrige-Fernando, E. Cavedon, J. Manso, M. Iacobone, E. Casal-Ide, F. Galuppini, A. Fassina, G. Pennelli, F. Vianello, L. Bertazza, C. Mian “Prognostic significance of TERT promoter and BRAF mutations in cytologically suspicious or malignant thyroid nodules: a monocentric case series at a tertiary-level endocrinology unit” 29/05/2019-01/06/2019, 40° Congresso Nazionale della Società Italiana di Endocrinologia (SIE), Roma, Italia

Censi S, Barollo S, Grespan E, Watutantrige-Fernando S, Cavedon E, Manso J, Iacobone M, Casal Ide E, Galuppini F, Pennelli G, Vianello F, Bertazza L, Mian C “Significato prognostico delle mutazioni del promotore di TERT e di BRAF in una serie consecutiva monocentrica di citologici tiroidei TIR-4 e TIR-5” 22-24/11/2018, 12° Congresso nazionale dell’Associazione Italiana Tiroide (AIT), Catania, Italia

Censi S, Pandolfo G, Cavedon E, Watutantrige-Fernando S, Manso J, Franceschet G, Zaninotto M, Plebani M, MIan C, Camozzi V “Transient fall of bone markers and stable BMD and TBS values in the course of high-dose, short-term glucocorticoid therapy in patients with Graves orbitopathy, a small prospective pilot study”. 28/04/2018, Precision medicine in Endocrinologia, Congresso Triveneto della Società Italiana di Endocrinologia (SIE Triveneto), Verona, Italia.

Censi S, Manso J, Bodanza V, Gusella S, Cavedon E, Watutantrige-Fernando S, Barollo S, Bertazza L, Boscaro M, Cecchin D, MIan C. “Utilità del rapport image-to-background (IBR) in corso di scintigrafia tiroidea con 99mTc-sestamibi nella diagnosi differenziale della tireotossicosi indotta da amiodarone, risultati preliminari” 30/11-2/12/2017 11° Congresso nazionale dell’Associazione Italiana Tiroide (AIT), Torino, Italia.

Censi S, Bodanza V, Gusella S, Manso J, Cavedon E, Watutantrige-Ferando S, Cecchin D, Mian C. “The usefulness of Image-to-Background ratio (IBR) of 99mTC-SestaMIBI thyroid scan in the differential diagnosis of Amiodarone induced thyrotoxicosis, preliminary results.”. 21-24/06/2016, 39° Congresso Nazionale della Società Italiana di Endocrinologia (SIE), Roma, Italia

Censi S, Cavedon E, Bertazza L, Galuppini F, Watutantrige-Fernando S, De Lazzari P, Nacamulli D, Pennelli G, Fassina A, Iacobone M, Casal Ide E, Vianello F, Barollo S, Mian C. “Prevalenza e significato della mutazione del promotore di TERT in un’ampia serie monocentrica di citologie tiroidee indeterminate”. 28/01/2017, Congresso Triveneto della Società Italiana di Endocrinologia (SIE Triveneto), Trento, Italia.

Censi S, Barollo S, Cavedon E, Watutantrige-Fernando S, Regazzo D, Bertazza L, Pelizzo MR, Zambonin L, De Lazzari P, Nacamulli D, Scaroni C, Occhi G, Mian C. “AhR gene expression and function in papillary thyroid carcinoma”, 27-30/05/2015, 38° Congresso Nazionale della Società Italiana di Endocrinologia (SIE), Taormina, Italia.

Barollo S, Sensi F, Galuppini F, Cavedon E, Zambonin L, Watutantrige-Fernando S, Censi S, Boscaro M, Pennelli G, Bertazza L, Mian C. “Pathway MIR-375/YAP-1: nuovo fattore prognostico per il carcinoma midollare della tiroide”. 15-17/12/2016, 10° Congresso Nazionale dell’Associazione Italiana Tiroide (AIT), Cagliari, Italia

Watutantrige-Fernando F, Barollo S Bertazza L, Censi S, Cavedon E, Nacamulli D, Boscaro M, Galuppini F, Pennelli G Iacobone M, Vianello F, Mian C. “Studio clinico-molecolare di una serie di carcinomi papillari tiroidei con pattern hobnail”. 3-5/12/2015, 9° Congresso Nazionale dell’Associazione Italiana Tiroide (AIT), Udine, Italia

Cavedon E, Barollo S, Bertazza L, Censi S, Nacamulli D, Boscaro M, Mian C. “Impatto prognostico di mutazioni di RAS ed espressione di miR-224 nel carcinoma midollare della tiroide” 27-29/11/2014 8° Congresso Nazionale dell’Associazione Italiana Tiroide (AIT), Milano, Italia.

Barollo S, Bertazza L, Pennelli G, Cavedon E, Galuppini F, Zambonin L, Pelizzo MR, Cappellesso R, Fassina A, De Lazzari P, Censi S, Betterle C, Mian C. PDCD4 nuovo oncosoppressore nel carcinoma midollare tiroideo: correlazione con mir-21” 5-7/12/2013, 7° Congresso Nazionale dell’Associazione
Italiana Tiroide (AIT), Roma, Italia